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Upfront EGFR TKIs Selection: 1st, 2nd, or 3rd Generation?

Presenters

Prof. Keunchil Park, MD
Director of Innovative Cancer Medicine Institute
Prof. Keunchil Park, MD
  • 28 - 33 Mins

  • Self paced

    Upon completion you will earn a certificate

EGFR TKIs are not Equal: What RCTs tell us

As more EGFR TKIs become available for patients with NSCLC, the clinical decision on which agent to give patients becomes more complex. During a DIALOG webinar, Professor Keunchill Park (Korea) shared the most relevant RCT data on EGFR TKIs in NSCLC treatment, including the LUX-Lung 7, ARCHER 1050 and FLAURA studies.

Estimated Time of Completion: 5-6 mins.

EGFR TKIs, are they all the same in the real world?

The treatment of EGFR-mutant NSCLC using EGFR TKIs has become established, leading to a substantial amount of real-world data on this treatment strategy over the years. During a DIALOG webinar, Professor Keunchill Park (Korea) shared the most recent collection of real-world data on the different EGFR TKIs in NSCLC treatment, including recent Asian data from Korea, Taiwan and Japan.

Estimated Time of Completion: 5-6 mins.

Treating NSCLC with T790m mutations

T790m mutation is the most common mechanism of resistance to first- and second-generation EGFR TKIs. During a DIALOG webinar, Professor Keunchill Park (Korea) discussed the emerging treatment strategies to assess and manage NSCLC patients T790m mutations.

Estimated Time of Completion: 5-6 mins.

Maximizing EGFR TKI treatment in NSCLC

In patients with EGFR mutant NSCLC, prolonging time TTF and chemo-free time is a valuable goal among patients. During a DIALOG webinar, Professor Keunchill Park (Korea) highlighted the role of proper treatment sequencing in achieving maximal TTF and prolonging survival in NSCLC.

Estimated Time of Completion: 8-9 mins.

First-line EGFR TKI choice to optimize treatment sequence

The choice of first-line EGFR TKI has an impact on the overall treatment sequence and the eventual clinical outcome of patients with EGFR mutant NSCLC. During a DIALOG webinar, Professor Keunchill Park (Korea) underscored the role of second-generation EGFR TKIs in maximizing TTF and extending survival in NSCLC.

Estimated Time of Completion: 5-6 mins.

About the speaker

Professor Keunchil Park is currently the Director of Innovative Cancer Medicine Institute and Professor Emeritus in the Department of Hematology-Oncology in Samsung Medical Center, Sungkyunkwan University School of Medicine.

Upfront EGFR TKIs Selection: 1st, 2, or 3rd Generation? Course Outline

  • Differentiation between EGFR TKIs Adherence to antihypertensive treatment is poor
  • Differentiation between EGFR TKIs: More real-world data Reasons for Insufficient Pressure Control
  • T790m mutation Improving Medical Adherence
  • Treatment sequence: Afatinib followed by Osimertinib
  • Treatment sequence: Afatinib vs 1st-gen TKI as first-line

PC-PH-103430 / March 2022